Human Protein-Protein Interaction Network
Undirected, weighted network of human protein interactions. Nodes represent proteins, edges represent confirmed physical interactions. Edge weights represent confidence scores (0-1) from interaction prediction methods and experimental evidence aggregation. Heavily connected biological network useful for studying scale-free properties in real biological systems.
npx keepset fetch ppi-human
- Nodes
- 20,744
- Edges
- 987,845
- Size
- 180.1 MiB
Fetch and preview this dataset on this page, or download the result as JSON. The command line fetches it without a browser.
Overview
Sources and provenance
Citations
- Szklarczyk et al. (2019). STRING: functional protein association networks. Nature Methods.
Recipe
| Source | #0 |
|---|
| Archive | zip |
|---|
| Member | matching BIOGRID-ORGANISM-Homo_sapiens-[0-9.]+\.tab3\.txt |
|---|
| Parser format | "edge-list" |
|---|
| Parser encoding | "utf-8" |
|---|
| Parser delimiter | "tab" |
|---|
| Parser skipLines | 0 |
|---|
| Parser commentPrefixes | ["#"] |
|---|
| Parser sourceColumn | 3 |
|---|
| Parser targetColumn | 4 |
|---|
| Parser where | [{"column":12,"equals":"physical"},{"column":15,"equals":"9606"},{"column":16,"equals":"9606"}] |
|---|
Crosswalk
keepset/topology to graph/v1, as a crossmap crosswalk.
| Rule | From | To | Direction |
|---|
| move | meta | meta | both |
| move | nodes[].id | nodes[].id | both |
| move | edges[].source | edges[].source | both |
| move | edges[].target | edges[].target | both |
Expected counts
Properties
| Components | 3 |
|---|
| Connected | no |
|---|
| Cyclic | yes |
|---|
| Density | 0.002657 |
|---|
| Directed | no |
|---|
| Download bytes | 180.1 MiB |
|---|
| Edge types | 1 |
|---|
| Heterogeneous | yes |
|---|
| Multigraph | no |
|---|
| Node types | 1 |
|---|
| Raw bytes | 0 B |
|---|
| Self loops | yes |
|---|
| Weighted | yes |
|---|