keepset

Hetionet

Heterogeneous biomedical knowledge graph integrating 29 public databases. Contains 11 node types (Compounds, Diseases, Genes, Proteins, etc.) connected by 24 edge types including compound-disease treatments, gene-disease associations, and protein interactions. Designed for drug repurposing and biomedical discovery.

npx keepset fetch hetionet

Nodes
45,158
Edges
2,250,197
Size
11.8 MiB

Fetch and preview this dataset on this page, or download the result as JSON. The command line fetches it without a browser.

Overview

Idhetionet
Categorygraph/v1
Kindgraph
DomainBiomedical knowledge graph
Tagsheterogeneous
LicenceCC0 1.0 for original content, with each integrated source under its own licence
Cataloguekeepset 1.33.0

Sources and provenance

#URLStatusRetrievedRead by recipePinned snapshotSHA-256
0https://media.githubusercontent.com/media/hetio/hetionet/main/hetnet/tsv/hetionet-v1.0-edges.sif.gzlive2026-03-03yes20261022011839raw611f0411ac66

Citations

Recipe

Source#0
Archivegzip
Parser format"kg-triples"
Parser encoding"utf-8"
Parser delimiter"tab"
Parser order"head-relation-tail"
Parser header"names"
Parser quotedfalse

Crosswalk

keepset/relations to graph/v1, as a crossmap crosswalk.

RuleFromToDirection
movemetametaboth
movenodes[].idnodes[].idboth
moveedges[].sourceedges[].sourceboth
moveedges[].targetedges[].targetboth
moveedges[].typeedges[].typeboth

Expected counts

Edges2,250,197
Nodes45,158

Properties

Components1
Connectedyes
Cyclicyes
Density0.0003808
Directedyes
Download bytes11.8 MiB
Edge types24
Heterogeneousyes
Multigraphyes
Node types1
Raw bytes0 B
Self loopsno
Weightedno